Paper Title
Design and Analysis of Automated Degasser for Pharmaceutical Applications
Abstract
In pharmaceutical industry, degassing is widely used to remove dissolved oxygen from various solutions. This is
performed for various reasons including the restriction of growth of bacteria in the solution. This paper discusses design of an
automatic degassing system which monitors the dissolved oxygen quantity in any solution, continuously without human
intervention. The entire process of transferring the solution to degassing tank is fully automated, including start and stop of
degassing process and transfer of the degassed solution from degassing chamber to storage tank where it is maintained in its
degassed state and at a certain temperature. In this process, the quantity of dissolved oxygen, pH value, and temperature values at
various steps are monitored through various sensors. The sensor signals are used to control the process through an indigenously
developed Programmable Logic Control (PLC) code that executes actuation signals for the operation of field actuators such as
valves, stirrer, and pumps. The process can be operated in batch as well as continuous manner.
Keywords - Degassing, Dissolved oxygen, Human Machine Interface, Programmable Logic Control