Numerical Simulation Of Pulsatile Blood Flow In An Idealized Curved Section Of A Human Coronary Artery
The computational fluid dynamics simulations (CFD) has been carried in an idealized curved section of human
coronary artery using multiphase transient, pulsatile and non-Newtonian flow. The study of behavior of affected flow regions
of blood cells in arteries has significant impact in understanding atherogenesis. The non-Newtonian model is applied to fluid
dynamics approach consisting of plasma, RBCs, and leukocytes was studied to arrive at numerical simulations of local
hemodynamics in a flow regime. This CFD model study helps in finding the flow patterns, phase distributions and wall shear
simulate and to examine the behavior of fluid, and find out that it depends on both volume fractions and shear rate of RBCs
and leukocytes. The migration and segregation of blood cells in arteries were computed. When higher leukocyte
concentration was predicted, it was correlated with relatively low WSS near the curvature having a high wall shear stress.
This action is mainly due to flow-dependent particle interactions of the leukocytes with RBCs in pulsatile flow. This
multiphase hemodynamic analysis will be of great help in following the mechanism of plaque formation in arteries with in
vivo complex flow conditions.
Keywords- Multiphase Flow; Non-Newtonian; Computational Fluid Dynamics; Wall Shear Stress; Particle Build up